Procavia_capensisFamily: MMR_HSR1 Number of Genes: 55
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RAB30
-
-
-
-
-
NOA1
-
ARFRP1
-
GNL3
-
SEPT7
-
SAR1B
-
RAB11A
-
ERAL1
-
SEPT2
-
-
-
RRAGA
-
SEPT11
-
GTPBP8
-
ARL14
-
-
-
ARL10
-
GNL3L
-
LSG1
-
ARF4
-
SEPT9
-
-
-
RAB6A
-
RAB36
-
MTIF2
-
ARL8A
-
EHD2
-
-
-
EHD3
-
RASL11B
-
SEPT1
-
ARL3
-
RAB9A
-
RAB33B
-
-
-
IRGC
-
DRG2
-
ARL4D
-
RAB9B
-
SRPRB
-
RAB6B
-
EHD4
-
-
-
NRAS
-
RAB25
-
RAB12
-
DRG1
-
RAB1B
-
GNL2
-
NKIRAS2
-
GTPBP10
-
RAB11B
-
RAB5C
-
RAB34
-

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.