Haplochromis_burtoniFamily: DEAD Number of Genes: 72
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
skiv2l
ddx28
ddx18
ddx19
recql
ddx4
dhx58 (1 of many)
dhx58 (1 of many)
helq
-
polq
-
DDX5
ddx39aa
dhx9
eif4a1b
ifih1
dhx57
dhx15
zgc:158828
dhx8
dhx30
mtrex
dhx29
zgc:193690
ddx59
-
hfm1
-
YTHDC2
-
ddx51
ercc6l
ddx20
ddx27
cmss1
ddx42
DHX15 (1 of many)
ddx49
-
ddx6
dhx16
DDX41
snrnp200
ddx55
ddx43
ddx23
ddx10
dhx38
dhx37
ddx1
eif4a3
ascc3
dhx36
ddx56
ddx52
blm
-
ddx21
ddx61
eif4a2
dicer1
recql4
ddx31
DDX39A
recql5
-
tdrd12
-
ddx46
si:dkey-156n14.5
ddx24
ddx5
-
-
ddx47
DDX17
dhx40

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.