Nannospalax_galiliFamily: DEAD Number of Genes: 73
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Smarca5
Ascc3
Eif4a2
-
-
Dhx16
Blm
-
Ddx58
Recql5
Ddx17
Ddx50
Recql4
Ddx18
Ddx25
Smarca1
Dhx57
Dicer1
Ddx10
Ddx39
-
Mtrex
Ifih1
Ddx4
-
Dhx38
Dhx37
Dhx40
-
-
Ddx43
Dhx36
Ddx28
Ddx1
Ercc6l2
-
Dhx15
Ddx5
Ddx6
Dhx58
Dhx33
Fancm
Ythdc2
-
-
-
Ddx3x
Dhx29
Eif4a1
Wrn
Ddx56
Ttf2
Ddx23
Ddx19a
Ddx49
Ddx46
Ddx47
Cmss1
-
-
-
Ddx55
Ddx52
Ddx51
Ddx31
Ddx54
Ddx59
Tdrd9
Ddx42
Snrnp200
Ddx41
Ddx21
-
-
Ddx39b
Ddx20
Ddx27
Dhx30
Polq

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.