Anolis_carolinensisFamily: DEAD Number of Genes: 64
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX25
DHX15
SNRNP200
-
DDX58
-
DDX46
-
DDX18
RAD54L
SMARCA5
WRN
-
DDX42
-
DDX54
DDX10
EIF4A1
-
DDX41
DHX57
DDX59
DDX20
DDX52
RECQL5
DHX36
EIF4A2
YTHDC2
DHX38
-
-
DDX24
DDX28
DDX21
ASCC3
RECQL4
DDX47
DDX39A
HELQ
TDRD9
DHX16
DDX1
CMSS1
SMARCA1
POLQ
SKIV2L
DDX39B
DHX40
DHX58
DICER1
DHX8
IFIH1
BLM
EIF4A3
DHX37
DDX4
DHX33
MTREX
DDX55
DHX29
DDX60
DDX6
RECQL
DHX30
-
-
-
DDX23
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.