Carlito_syrichtaFamily: DEAD Number of Genes: 79
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX20
DDX17
DDX42
RAD54L
DICER1
DHX36
-
DDX18
DDX47
DDX52
DDX46
DDX10
TDRD9
DHX29
DDX43
DDX3X
DHX57
DDX50
DDX58
SMARCA1
EIF4A1
DHX30
DDX23
IFIH1
DHX33
-
ASCC3
-
MTREX
DDX55
DDX54
DHX9
DDX56
EIF4A3
DDX31
RECQL
CMSS1
POLQ
YTHDC2
SMARCA5
-
SNRNP200
DDX21
DHX15
-
DDX4
DHX38
-
-
RECQL4
-
SKIV2L
DDX5
BLM
-
WRN
HELQ
EIF4A2
DDX60L
DDX59
ERCC6L2
-
HFM1
DDX25
-
-
DDX19A
DDX6
DDX49
-
-
DHX37
-
-
-
-
DHX16
DDX39A
DDX27
-
-
-
RECQL5
DDX41
DDX51
-
DHX40
-
-
-
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.