Chlorocebus_sabaeusFamily: DEAD Number of Genes: 73
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RAD54L
DDX20
-
DDX51
DHX37
DDX55
DDX25
DDX54
DDX6
DDX10
DHX58
DDX60L
DDX60
SMARCA5
DDX42
DDX5
DHX38
HELQ
DDX19A
-
-
RECQL5
DDX49
BRIP1
CMSS1
DDX52
DDX23
DDX39A
DDX17
POLQ
DDX50
-
DDX1
RECQL
DHX16
RECQL4
SMARCA1
DDX39B
DDX47
DDX41
SKIV2L
EIF4A2
DDX58
TDRD9
DICER1
DDX24
EIF4A1
DHX36
DHX57
DHX9
DHX33
-
DDX59
DDX3X
-
DDX43
ASCC3
YTHDC2
DDX31
DDX27
FANCM
IFIH1
DDX56
WRN
DHX30
DDX4
MTREX
DDX18
DHX29
DHX15
BLM
SNRNP200
DDX3Y
DDX28
DDX53

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.