Felis_catusFamily: DEAD Number of Genes: 73
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX23
DHX30
DDX18
DDX58
DHX40
DDX27
DDX41
TTF2
DDX21
DHX58
RAD54L
DDX42
DDX5
DICER1
DDX55
DDX39B
SKIV2L
SMARCA5
DDX1
DHX36
DDX25
RECQL5
DHX38
BLM
DHX57
DDX31
-
DDX10
DHX16
DHX29
EIF4A3
DHX15
DDX19A
DDX49
HELQ
DDX24
DDX56
DDX52
MTREX
SNRNP200
DDX60
DDX51
DDX4
DDX50
DDX28
DDX39A
TDRD9
EIF4A2
DDX47
DHX37
DHX33
SMARCA1
DHX9
-
-
POLQ
IFIH1
WRN
EIF4A1
DDX3X
DDX20
DDX46
DDX59
DDX54
HFM1
DDX6
-
-
-
RECQL
-
-
ASCC3
DDX17
-
YTHDC2
CMSS1

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.