Macaca_mulattaFamily: DEAD Number of Genes: 79
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DHX38
SKIV2L
SMARCA5
DDX21
DDX50
DDX60
DDX56
-
CMSS1
DDX52
IFIH1
DDX60L
EIF4A2
DHX30
DDX59
DDX17
DDX31
-
DHX9
DDX39A
TDRD9
DHX33
HFM1
-
-
-
-
DDX25
DDX24
POLQ
DDX23
SMARCA1
DDX39B
BRIP1
DDX5
EIF4A3
DHX15
DHX29
MTREX
DDX28
RECQL
DHX36
RAD54L
DDX58
DDX46
DDX55
-
DDX10
DHX58
HELQ
RECQL4
-
-
-
FANCM
DDX42
DDX41
DDX4
DDX3X
DHX37
DDX47
DDX6
BLM
DDX43
-
-
DHX16
-
DHX57
DDX18
RECQL5
DDX54
ASCC3
WRN
SNRNP200
DDX49
DICER1
DDX1
DDX27
-
-
-
-
-
-
DDX3Y
-
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.