Otolemur_garnettiiFamily: DEAD Number of Genes: 79
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DHX57
DDX52
RECQL5
DDX17
-
DHX33
YTHDC2
DDX50
-
-
-
CMSS1
DDX27
DHX9
DHX29
MTREX
FANCM
DDX47
DDX31
DDX54
SMARCA1
RECQL
DDX3X
BLM
-
DDX24
DDX42
SNRNP200
DDX18
-
DDX4
-
TDRD9
DHX40
DDX6
-
DDX49
DHX16
DHX38
DDX1
DDX59
-
DDX55
SKIV2L
WRN
SMARCA5
ASCC3
-
DDX56
-
DDX20
DHX37
DDX58
DICER1
EIF4A2
DDX10
-
-
DHX36
-
-
-
DHX30
IFIH1
RECQL4
DDX25
DDX43
HELQ
-
POLQ
DDX23
DDX28
DHX58
-
-
-
-
-
-
-
-
-
-
DDX51
-
-
-
-
-
-
HFM1
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.