Pundamilia_nyerereiFamily: DEAD Number of Genes: 71
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX41
DDX39A
zgc:158828
ddx10
eif4a2
hfm1
-
-
ifih1
ddx55
-
si:dkey-156n14.5
dhx29
mtrex
ddx19
dhx15
YTHDC2
dhx57
-
-
DHX15 (1 of many)
dhx37
dhx9
ddx6
recql4
-
ddx43
eif4a1b
ddx39b
helq
dhx58 (1 of many)
-
dhx58 (1 of many)
blm
smarca5
-
ddx46
-
ercc6l
-
dhx38
dhx40
cmss1
ddx31
ddx1
ddx42
dhx30
ddx20
ddx27
ddx61
ddx21
-
recql
ddx18
-
ddx49
eif4a3
recql5
-
snrnp200
DDX5
skiv2l
dicer1
dhx16
-
-
ddx28
ascc3
ddx56
-
ddx59
ddx47
ddx52
ddx5
ddx23
zgc:193690
ddx4
-
tdrd9
ddx24
tdrd12
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.