Ursus_maritimusFamily: DEAD Number of Genes: 71
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DHX37
DDX6
-
-
RECQL
DDX25
CMSS1
-
DDX47
DDX51
-
DICER1
DHX15
DDX55
SMARCA1
EIF4A2
DDX39A
DDX24
-
DDX58
DDX49
DDX23
WRN
DDX10
-
-
DDX50
DDX21
HELQ
BLM
RECQL5
DDX4
MTREX
DDX56
-
DHX29
DDX54
DDX3Y
-
-
DHX36
IFIH1
-
SNRNP200
SKIV2L
DHX57
DDX18
DDX20
-
EIF4A3
-
-
DDX39B
-
SMARCA5
DHX9
-
DDX31
DDX3X
-
DDX42
DDX46
DDX5
DHX38
DDX28
-
RECQL4
DHX16
DDX60
ASCC3
DHX40
DHX58
DDX1
YTHDC2
DDX41
DDX27
TDRD9
POLQ
DDX59

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.