Cebus_capucinusFamily: DEAD Number of Genes: 84
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
MTREX
DHX15
-
-
DDX42
-
-
DDX55
-
-
TDRD9
DHX58
DHX9
-
DDX54
BLM
DDX52
-
WRN
DDX3X
DDX17
-
DDX10
ASCC3
BRIP1
DDX56
DHX16
DDX47
RAD54L
DDX31
SKIV2L
DDX21
POLQ
FANCM
DDX59
DDX46
DHX29
DDX20
ERCC6L2
-
DICER1
SMARCA5
IFIH1
DDX25
DDX39B
DHX33
-
-
RECQL
DHX57
DHX40
DDX4
-
-
-
DDX23
DDX27
DDX1
DDX60L
-
-
-
DDX50
-
SMARCA1
DDX51
DHX38
RECQL5
DHX30
-
HFM1
-
-
DHX37
SNRNP200
DDX60
CMSS1
DDX39A
DHX36
-
-
RECQL4
DDX49
DDX24
EIF4A3
DDX41
-
DDX58
HELQ
-
-
DDX43
-
-
YTHDC2
DDX5

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.