Gallus_gallusFamily: DEAD Number of Genes: 59
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
YTHDC2
DDX42
DHX38
DDX20
DDX59
RECQL5
DHX37
DDX49
DDX55
DDX5
-
-
DDX52
DDX46
-
DDX27
DDX54
BLM
SMARCA1
EIF4A3
EIF4A2
DDX60
SMARCA5
RAD54L
DDX24
DICER1
HELQ
DDX47
DDX18
RECQL
DHX15
DHX29
MTREX
DDX4
POLQ
CHD1L
CMSS1
ASCC3
-
-
DDX3X
DDX1
DDX10
DHX58
FANCM
DDX23
DDX51
DDX6
SKIV2L
-
DDX17
DHX30
DDX25
DDX19B
WRN
IFIH1
DDX31
-
-
-
DDX41
DHX36
DDX28

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.