Phascolarctos_cinereusFamily: DEAD Number of Genes: 69
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DHX36
-
DDX49
DDX17
DHX38
DDX41
-
-
DDX10
DHX9
SMARCA5
DHX15
YTHDC2
-
-
DDX51
-
-
BLM
-
DDX27
DDX42
DDX46
DDX56
DDX25
DDX1
DDX55
DDX6
-
EIF4A2
DHX30
HFM1
-
DDX5
DHX16
SMARCA1
-
DDX21
CMSS1
DDX50
ASCC3
DDX39B
DDX52
-
-
DICER1
SKIV2L
DHX37
DDX31
HELQ
DHX33
WRN
LGP2
RECQL5
DHX57
-
DHX40
RECQL
SNRNP200
-
-
MTREX
DDX4
-
DHX29
DDX24
DDX23
DDX20
-
-
EIF4A1
DDX18
RAD54L
RIG-I
DDX39A
DDX47
IFIH1
DDX59

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.