Poecilia_mexicanaFamily: DEAD Number of Genes: 70
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
blm
ddx19
ddx56
eif4a1b
ddx52
ddx4
DDX41
zgc:158828
dhx37
ddx10
ddx43
ddx27
ddx20
tdrd12
-
ddx24
-
dhx16
-
skiv2l
eif4a3
dhx8
rad54l
dhx36
dhx40
-
DDX39A
-
-
mtrex
-
ddx42
-
ddx54
ddx1
ddx51
ddx28
-
dhx58
recql4
DDX5
dhx33
recql
ddx46
-
dicer1
helq
ddx21
ddx18
YTHDC2
ddx23
dhx38
ifih1
ddx49
dhx15 (1 of many)
-
ddx31
ddx5
eif4a2
ddx47
zgc:193690 (1 of many)
ddx59
DHX15
hfm1
-
ddx6
smarca5
dhx9
ddx55
cmss1
snrnp200
-
dhx57
dhx30
zgc:193690 (1 of many)
-
recql5

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.