Rhinopithecus_roxellanaFamily: DEAD Number of Genes: 83
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX5
-
-
DDX18
-
-
DHX57
RECQL
RAD54L
-
-
-
DDX27
DDX55
DDX47
DDX39A
DHX38
-
-
FANCM
-
-
DDX23
ERCC6L2
DDX46
DDX58
DDX54
SMARCA5
DDX42
DDX51
DDX3X
-
DDX20
DDX60
-
-
IFIH1
DDX1
DDX43
DDX10
DICER1
DHX16
DDX50
EIF4A1
DDX49
DDX6
-
-
DDX21
-
DDX25
SMARCA1
-
-
DDX52
DDX41
DHX58
-
SKIV2L
DHX36
DDX3Y
TDRD9
BLM
-
-
DHX33
DHX15
DHX30
-
-
YTHDC2
DDX39B
DDX60L
MTREX
RECQL4
DHX37
DDX59
EIF4A3
CMSS1
RECQL5
DHX29
DDX31
DDX56
DHX9
HELQ
POLQ
DDX19A
DDX17
WRN
DDX4
ASCC3
HFM1
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.