Pan_troglodytesFamily: MMR_HSR1 Number of Genes: 134
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
MFN2
GNL2
NRAS
RAB13
RAB25
ARL8A
ARF1
GTPBP4
-
ARL5B
RAB18
SAR1A
-
-
EHD1
RAB1B
RAB30
CRACR2A
RERG
KRAS
DNM1L
-
RAB5B
ARL1
RAB35
RASL11A
ARL11
-
-
-
-
EHD4
SRL
SEPT12
SEPT1
DRG2
-
RAB34
ERAL1
NKIRAS2
RAB5C
SEPT4
RAB12
EEF2
RAB11B
GTPBP3
IRGC
EHD2
-
DNAJC27
GPN1
EHD3
MTIF2
RAB1A
EIF5B
ARL5A
OLA1
ARL4C
-
MTG2
ARFRP1
-
-
RAB36
DRG1
-
SEPT3
-
-
ARL8B
-
RAB5A
GNL3
ARF4
ARL6
GTPBP8
RABL3
EEFSEC
RAB7A
SRPRB
LSG1
GUF1
RASL11B
NOA1
SEPT11
RAB33B
SEPT8
SAR1B
GNL1
SEPT7
SEPT14
-
GTPBP10
ARF5
GIMAP8
-
GIMAP7
GIMAP4
GIMAP6
RAB2A
RRAGA
-
RASEF
RAB14
RAB9A
-
-
-
RRAGB
SEPT6
SEPT2
RAB9B
-
-
GIMAP2
GIMAP1
-
HRAS
ARL2
RAB39B
-
RAB23
-
-
RAB6A
-
-
RAB22A
SEPT9
-
-
-
RAB44
-
-
RHEB
EHD2
ARL10
-
-
-
-
-
-
-
-
-
RAB6B
-
ARL14
ARL4D
ARL4A
-
-
-
GNL3L
GTPBP6
-
-
-
-
-
-
-
-

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.