Monodelphis_domesticaFamily: DEAD Number of Genes: 70
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
SMARCA5
DHX15
DDX18
DDX20
-
CMSS1
DDX24
DDX39A
DDX52
DHX38
DDX60
DDX54
-
-
DDX5
DDX49
DDX25
DDX41
DDX28
-
IFIH1
DHX9
EIF4A1
FANCM
RECQL5
SNRNP200
DHX57
DDX17
-
-
DDX23
-
DDX1
DDX21
-
DDX50
-
ERCC6L
-
RECQL4
-
DDX55
DDX31
DICER1
DDX59
-
DDX6
DHX30
DDX46
-
-
DHX40
-
DDX10
DHX58
SKIV2L
DDX51
YTHDC2
DHX37
DDX39B
-
DHX36
DHX16
DDX56
DDX27
DHX33
RECQL
ASCC3
DDX47
POLQ
-
WRN
BLM
DHX29
MTREX
DDX4
HELQ
-
EIF4A2

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.