Neolamprologus_brichardiFamily: DEAD Number of Genes: 69
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
dhx57
YTHDC2
ddx5
-
ddx28
-
ddx47
ddx39aa
recql5
-
ddx59
dhx36
DDX17
-
zgc:193690
ddx56
hfm1
-
DDX5 (1 of many)
cmss1
eif4a1b (1 of many)
-
eif4a1b (1 of many)
-
ddx6 (1 of many)
-
ddx6 (1 of many)
-
smarca5
ddx42
eif4a2
ddx54
-
dhx16
ddx21
ddx27
-
ddx24
ddx52
ddx46
tdrd9
DDX39A
dhx38
ddx43
mtrex
dhx30
ddx51
DHX15 (1 of many)
ddx4
-
ifih1
zgc:158828
ddx19
-
DDX41
ddx61
-
-
ddx10
-
-
snrnp200
dhx40
dhx58 (1 of many)
dhx58 (1 of many)
skiv2l
ddx55
dhx37
-
blm
-
ddx20
-
ddx1
-
recql
eif4a3
ddx49
ascc3
-
dicer1
ddx23
dhx8
-
-
ddx31

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.