Canis_lupus_dingoFamily: DEAD Number of Genes: 76
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RECQL5
SKIV2L
WRN
SMARCA1
-
-
DDX17
YTHDC2
DDX52
IFIH1
DHX36
-
-
POLQ
DDX46
EIF4A2
DDX47
DDX10
DDX39A
EIF4A1
RECQL
DDX20
EIF4A3
TDRD9
-
-
DDX51
HELQ
DDX25
DDX41
DDX49
-
DHX37
-
-
DDX6
DDX23
-
-
DHX58
DDX18
DICER1
DDX24
DDX58
-
-
DHX9
RAD54L
DDX55
BLM
DHX33
ASCC3
DDX27
DHX16
DDX54
DDX59
DDX56
DDX28
-
SNRNP200
DHX30
DHX38
DDX39B
-
DDX19A
-
-
-
DHX57
-
-
DDX4
MTREX
DHX29
DDX31
SMARCA5
-
-
DDX50
DHX40
DDX1
DDX5
DDX42
DDX3X
DHX15

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.