Taeniopygia_guttataFamily: DEAD Number of Genes: 64
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
DDX41
ERCC6L2
-
DDX25
-
-
-
DDX58
-
WRN
-
DDX42
-
-
EIF4A3
HELQ
-
SMARCA5
-
DHX29
MTREX
DHX58
-
DDX4
DHX8
-
-
-
-
-
-
DDX59
DDX5
-
-
-
DDX31
-
-
DDX27
HFM1
-
-
IFIH1
-
DHX40
DHX38
RAD54L
-
-
-
RECQL5
-
-
-
DDX54
-
DDX47
DHX15
-
-
-
DDX51
-
DDX17
EIF4A2
DHX36
-
DDX18
-
RECQL
-
ASCC3
DDX10
-
-
DICER1
-
-
DDX1
-
-
-
-
-
CMSS1
-
DDX20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
DDX6
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.