Bos_taurusFamily: MMR_HSR1 Number of Genes: 133
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RAB6A
GUF1
-
RAB6B
RAB2A
SRL
SEPT7
-
EHD3
RERG
ARL2
ARL5A
RAB30
RAB11B
SEPT2
SEPT9
NKIRAS2
ARL4A
RAB33B
RAB15
GNL2
GTPBP3
EEF2
ARL3
RABL2B
-
MFN2
RAB23
DRG2
GTPBP8
ARL8A
ARF2
EHD4
OLA1
RAB5C
ARFRP1
ARF1
-
-
SEPT5
LSG1
GIMAP7
-
SEPT8
DRG1
SEPT14
ARF5
KRAS
GIMAP7
RAB18
ARL6
RAB7A
RAB12
MFN1
RAB9A
NUGGC
DNM1L
ARL1
ARL8B
RRAGB
SEPT3
IRGC
RAB5B
GIMAP8
MTG2
GNL3
GTPBP4
SEPT4
MTIF2
ERAL1
IFI47
RABL3
ARF4
SEPT12
RAB1A
ARL4D
SAR1A
RAB36
-
ARL14
RAB13
RAB14
RAB22A
DNAJC27
RAB25
CRACR2A
RAB11A
NOA1A
RAB39B
RAB9B
HBS1L
-
RASL11B
EHD2
SEPT1
SAR1B
SEPT11
-
RASEF
RAB35
-
-
ARL10
GNL1
GIMAP7
EEFSEC
GNL3L
RHEB
GTPBP10
RRAGA
EIF5B
IFI44
RAB33A
-
-
ARL5B
SRPRB
-
RAB2B
RAB34
GIMAP4
RAB5A
RAB1B
-
RAB31
HRAS
NRAS
GIMD1
-
-
-
RAB44
EHD1
-
-
ARF3
-
-
-
-
-
-
GTPBP6
-

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.