Ursus_maritimusFamily: MMR_HSR1 Number of Genes: 112
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
GIMD1
GNL2
-
-
RAB36
-
-
GIMAP4
-
LSG1
GUK1
-
ARF1
RAB9B
GUF1
ARL5A
SRL
-
RERG
SEPT12
SEPT7
KRAS
RAB14
-
-
RASEF
-
RAB2B
DRG2
-
-
-
-
ARF6
-
EEF2
MFN1
EHD1
SEPT11
SAR1A
-
NOA1
EIF5B
-
-
-
-
RAB44
RAB6A
-
-
-
SEPT2
-
-
GIMAP8
ARL14
-
-
RAB1B
EHD4
SEPT1
ERAL1
NRAS
-
RAB33A
-
RAB11A
ARL4D
ARL4C
-
ARL5B
ARL6
RAB11B
-
CRACR2A
RAB33B
RAB7A
OLA1
-
-
SRPRB
-
DRG1
GTPBP4
RAB5B
MTIF2
-
ARL5C
RAB39B
SAR1B
SEPT8
-
-
-
-
RAB5A
RAB25
ARL11
GTPBP10
RAB23
GTPBP6
GNL1
GNL3L
-
ARL1
ARL8B
EHD3
GPN1
-
GNL3
RAB1A
ARF4
MFN2
MTG2
DNAJC27
SEPT4
NKIRAS2
IRGC
-
RAB5C
ARL3
RAB30
-
-
RRAGB
ARL10
-
-
-
-
-
-
-
RABL3

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.