Nomascus_leucogenysFamily: DEAD Number of Genes: 78
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
SNRNP200
DDX54
-
-
RECQL5
DDX43
DHX29
MTREX
DDX55
DDX4
DDX3X
DDX52
DDX47
DHX36
DDX56
DDX20
DDX42
FANCM
RECQL
POLQ
DHX16
SMARCA5
DHX38
DDX39B
DDX49
DHX30
SKIV2L
DDX60
DDX60L
EIF4A2
DDX27
-
DDX10
DDX6
DDX25
-
DDX46
-
HELQ
EIF4A1
HFM1
RECQL4
DDX21
DDX50
YTHDC2
DDX18
WRN
BLM
DDX41
DDX31
DDX39A
ASCC3
DDX1
DDX5
DDX17
SMARCA1
EIF4A3
DDX19A
TDRD9
DHX57
DHX15
ERCC6L2
DDX24
DICER1
DDX23
DHX9
DDX59
-
-
DHX58
IFIH1
-
-
-
-
-
-
-
-
-
CMSS1
-
-
-
-
-
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.