Octodon_degusFamily: DEAD Number of Genes: 77
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
ASCC3
DDX1
DHX36
-
-
-
-
-
-
-
TDRD9
-
-
-
DDX23
-
-
WRN
DDX25
-
-
-
-
-
-
-
-
-
DDX27
-
-
DDX18
-
-
YTHDC2
DDX42
POLQ
DDX6
SNRNP200
DDX41
RAD54L
DICER1
-
-
DDX51
-
DDX59
DHX37
DDX46
RECQL
EIF4A3
DDX49
DHX57
RECQL4
SMARCA1
DHX9
-
-
-
-
-
DDX47
DDX17
IFIH1
DHX40
-
DDX19A
-
-
DDX56
-
DDX54
BLM
-
DHX38
DDX31
-
DDX58
-
ERCC6L2
-
-
-
MTREX
-
SKIV2L
DHX29
-
-
DHX58
DDX39B
-
-
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.