Vulpes_vulpesFamily: DEAD Number of Genes: 73
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
YTHDC2
-
FANCM
-
DDX59
-
RECQL
-
TDRD9
-
DDX51
-
DDX47
-
DDX42
-
DDX5
-
BLM
-
RAD54L
-
DDX49
-
-
-
SMARCA1
-
DHX9
-
DHX16
-
DDX54
-
-
-
RECQL5
-
DDX3X
-
DDX56
-
-
-
DDX28
-
DDX1
-
EIF4A2
-
DHX15
-
DHX40
-
-
-
ASCC3
-
DDX10
-
HELQ
-
DDX20
-
-
-
SMARCA5
-
DHX38
-
DDX46
-
EIF4A3
-
-
-
IFIH1
-
DDX24
-
DHX57
-
-
-
DICER1
-
DDX39B
-
DDX23
-
WRN
-
DDX25
-
DDX52
-
DDX50
-
DDX21
-
HFM1
-
DHX58
-
DDX58
-
DHX29
-
MTREX
-
DDX4
-
-
-
DDX27
-
POLQ
-
DDX17
-
SKIV2L
-
DDX60
-
DDX6
-
DHX36
-
DHX37
-
DDX41
-
SNRNP200
-
DDX39A
-
DHX33
-
DDX55
-
DDX31
-
DHX30
-
DDX3Y
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.