Ailuropoda_melanoleucaFamily: DEAD Number of Genes: 74
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX25
HFM1
-
EIF4A2
DDX1
DDX19A
SKIV2L
FANCM
DHX38
DHX9
DDX5
DDX42
DDX58
CMSS1
DDX31
-
-
HELQ
-
DDX20
RECQL4
IFIH1
DHX58
DHX33
-
DDX6
DICER1
YTHDC2
DDX3X
DDX23
-
DDX54
SNRNP200
DDX10
DDX39B
RECQL5
SMARCA5
DHX15
DDX17
DDX47
DDX49
DHX40
ERCC6L2
-
DHX36
DDX59
DDX18
DHX30
DDX52
DHX16
DDX39A
DDX60
DDX27
DDX51
DHX29
BLM
-
MTREX
DDX4
ASCC3
POLQ
EIF4A3
SMARCA1
DDX55
-
DHX37
DDX24
DHX57
RECQL
EIF4A1
DDX56
DDX46
DDX21
DDX50
DDX41
TDRD9
DDX28
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.