Dipodomys_ordiiFamily: DEAD Number of Genes: 66
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Ddx6
-
Ddx25
Ifih1
Ddx19a
-
Ddx21
Recql4
Polq
Rad54l
Wrn
Dhx16
Ddx17
Ddx54
Smarca5
Ddx24
Recql5
Ddx42
Ddx52
Ddx49
Ddx19b
Dhx36
Ddx5
Ddx39b
Ddx31
Dhx38
Ddx46
Snrnp200
Dicer1
Dhx40
Mtrex
Dhx58
Ythdc2
Ddx50
Ddx59
Dhx34
Ascc3
Smarca1
Fancm
Ddx41
Blm
Ddx18
Ddx20
-
Ddx4
Dhx9
Ddx23
Ddx1
Dhx37
-
Ddx39
Dhx15
Dhx57
Ddx27
Eif4a1
Dhx33
-
Ddx10
Hfm1
Tdrd9
Recql
-
-
-
-
Ddx58
-
Dhx30
Ddx28
Ddx3x
Ddx43

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.