Fukomys_damarensisFamily: DEAD Number of Genes: 76
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
ERCC6L2
-
DDX20
DHX33
DDX4
-
-
TDRD9
DDX55
SNRNP200
DHX36
-
-
EIF4A2
DDX56
DHX30
DDX21
DDX19A
DDX31
-
WRN
-
YTHDC2
FANCM
DHX37
SKIV2L
DHX57
SMARCA1
DDX17
-
DDX59
DHX15
DDX49
DDX39B
-
-
MTREX
ASCC3
-
-
DHX9
-
DDX6
RECQL5
CMSS1
BLM
IFIH1
DDX51
-
DDX3Y
POLQ
DDX24
-
DDX39A
DDX18
-
RECQL4
-
DHX38
-
DDX23
DHX40
DHX16
-
-
DDX41
DHX58
HELQ
-
-
-
DDX25
DDX27
-
DHX29
RECQL
DDX54
DDX42
-
EIF4A3
-
HFM1
SMARCA5
DDX46
DICER1
DDX1

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.