Myotis_lucifugusFamily: DEAD Number of Genes: 87
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
SMARCA5
SKIV2L
ERCC6L2
-
-
-
DHX29
CMSS1
MTREX
DDX24
DDX4
-
DHX15
DDX10
DDX39B
-
-
DHX36
ASCC3
DDX1
DDX58
DDX47
DDX27
-
DDX56
DHX40
DDX6
-
-
RAD54L
DICER1
-
-
RECQL
WRN
DDX28
YTHDC2
DDX41
FANCM
-
DDX60
-
-
POLQ
DDX25
-
DHX16
-
DDX5
IFIH1
-
DDX20
HFM1
DDX3X
SNRNP200
-
-
-
DHX9
RECQL4
DDX31
DDX42
TDRD9
DHX58
DDX49
-
-
DDX46
DDX17
-
-
DHX38
TTF2
DHX33
BLM
DHX57
RECQL5
EIF4A2
DDX59
HELQ
DDX50
-
DDX18
-
-
DDX21
-
-
-
-
-
-
-
-
-
-
-
DDX51
-
SMARCA1
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.