Pan_troglodytesFamily: DEAD Number of Genes: 89
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RAD54L
HFM1
DDX20
DHX9
DDX59
DDX50
DDX21
DDX10
DDX6
DDX25
RECQL
DDX23
DDX54
DDX55
DDX51
FANCM
DDX24
TDRD9
BLM
DDX28
DDX19B
-
-
DHX38
DHX33
EIF4A1
DDX52
DHX58
DDX42
DDX5
RECQL5
EIF4A3
DDX39A
DDX49
TDRD12
DDX1
DHX57
SNRNP200
DDX18
IFIH1
DDX27
DDX17
DHX30
CMSS1
POLQ
DHX36
EIF4A2
DHX15
HELQ
SMARCA5
DDX60
DDX60L
DHX29
MTREX
DDX4
YTHDC2
DDX46
DDX41
DHX16
SKIV2L
DDX43
ASCC3
DDX56
WRN
DDX58
DDX31
DDX3Y
DICER1
DDX53
DDX39B
DDX47
-
-
-
-
-
-
-
-
-
-
-
-
RECQL4
-
-
ERCC6L2
-
-
DDX3X
SMARCA1
-
-
-
-
DHX37
-
-
-
-
-
-
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.