Ictidomys_tridecemlineatusFamily: MMR_HSR1 Number of Genes: 118
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
GNL3
-
NUGGC
ARL4D
RAB25
EHD4
RAB15
RAB2B
ARF5
GTPBP8
SEPT14
-
SEPT1
GUF1
ARL14
ERAL1
NOA1
RAB9B
-
RASEF
RHEB
RRAGB
ARL10
EEF2
ARL4A
MFN1
GNL2
-
-
MFN2
DNAJC27
-
GTPBP3
-
RAB5C
SEPT11
GTPBP10
RAB33A
RAB36
-
ARL8B
KRAS
EHD1
-
LSG1
RAB5B
-
RAB23
RAB1B
-
-
ARL5C
-
RAB39B
-
GNL1
ARFRP1
SEPT12
SAR1A
SEPT3
SEPT2
-
RAB6B
-
EIF5B
ARL3
-
DRG2
RAB11A
OLA1
ARL1
ARL5A
RABL3
-
-
SEPT10
-
-
-
-
RAB30
-
-
-
CRACR2A
HRAS
SEPT7
SRPRB
-
-
NRAS
GNL3L
ARL4C
RAB6A
RERG
RASL11A
-
MTG2
RAB9A
GIMAP8
-
RAB34
RAB12
RAB14
-
-
ARL2
SEPT8
GUK1
RAB5A
GIMD1
-
-
RAB33B
RASL11B
ARL5B
MTIF2
EHD3
ERAS
RAB7A
SEPT4
ARL6
IRGC
-
-
RAB11B

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.