Equus_caballusFamily: DEAD Number of Genes: 79
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
WRN
DHX38
DDX6
ERCC6L
SMARCA5
DDX31
DICER1
DDX28
-
DDX59
DHX37
RECQL5
DDX39B
IFIH1
DDX19A
-
DHX16
RAD54L
DDX24
DDX25
DDX41
DDX3X
DHX33
DDX10
DDX21
DDX5
DDX55
BLM
DHX58
DHX9
ASCC3
SMARCA1
DDX49
DDX52
TTF2
DDX54
DDX20
POLQ
CMSS1
DHX30
DDX18
EIF4A3
DDX1
DDX23
-
DDX43
DDX46
DHX40
RECQL4
FANCM
DHX57
DDX51
-
IGHMBP2
SNRNP200
DDX56
YTHDC2
HELQ
DDX27
EIF4A2
EIF4A1
SKIV2L
DDX58
DDX42
DDX50
DHX15
DDX4
DDX47
MTREX
TDRD9
HFM1
DDX60L
DDX60
DHX29
BRIP1
RECQL
DHX36
DDX17
-
-
DDX53
DDX39A

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.