Microcebus_murinusFamily: DEAD Number of Genes: 84
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX19A
TDRD9
DDX1
DDX27
RECQL
RAD54L
-
DDX49
-
SMARCA5
YTHDC2
DDX25
-
SNRNP200
DHX37
IFIH1
DDX56
FANCM
DDX55
DDX58
RECQL5
DDX41
DHX9
DDX24
DHX30
ASCC3
-
-
-
DDX5
DDX42
DDX47
DDX31
WRN
DHX38
DDX20
DDX6
DDX17
DICER1
DHX58
-
-
DDX59
DDX54
-
-
DHX33
DHX29
MTREX
DDX60
EIF4A1
DHX16
-
DDX39A
DHX15
SMARCA1
RECQL4
-
DDX43
DDX39B
DDX50
DDX23
-
-
DHX40
-
-
DHX57
DDX46
ERCC6L2
-
-
-
DDX3X
-
-
BLM
-
DDX10
DDX51
HFM1
-
-
-
-
-
-
-
-
-
-
-
-
SKIV2L
-
CMSS1
-
DHX36
POLQ

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.