Microtus_ochrogasterFamily: DEAD Number of Genes: 81
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Ddx1
Ddx50
Rad54l
Ddx6
-
Ddx25
D1Pas1
-
Dhx37
Dhx15
Ddx47
-
Ascc3
Ddx58
Dhx36
Eif4a1
Recql
Ddx19b
-
Ttf2
-
-
Fancm
Smarca1
Recql4
Ddx52
Ddx28
Ddx10
Dhx30
Ddx41
Dhx29
Dhx16
Ddx17
Ddx54
Ddx39b
Ifih1
-
Ythdc2
Snrnp200
Ddx5
Ddx46
-
-
-
Ddx20
Ddx43
Ddx24
Ddx4
-
-
Wrn
Ddx3x
Skiv2l
Helq
Hfm1
Dhx57
Ddx42
Dhx33
Blm
Ddx59
Ddx56
Dhx38
Ddx39
Polq
-
Tdrd9
Ddx19a
-
Dicer1
Ddx49
Ddx23
Dhx58
Dhx9
Ddx27
Recql5
Mtrex
-
-
Ddx21
Ddx31
Ddx55
Ercc6l
-
-
Eif4a2
Cmss1
Dhx40

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.