Cavia_porcellusFamily: DEAD Number of Genes: 75
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
YTHDC2
DHX30
DDX10
DDX52
SKIV2L
FANCM
DDX58
BLM
DDX27
-
SMARCA5
DDX39B
TDRD9
-
-
WRN
DDX23
DDX56
DHX40
-
DICER1
DDX4
-
-
DDX42
DDX24
DHX15
EIF4A3
-
RAD54L
SNRNP200
DDX5
IFIH1
HFM1
DDX18
DHX36
DDX60
DDX59
DDX39A
DDX41
DHX57
HELQ
MTREX
-
DDX55
Ddx6
-
DDX46
DDX25
DDX17
RECQL5
-
SMARCA1
DDX49
DDX28
-
DHX38
ASCC3
DDX31
CMSS1
DHX16
DDX21
RECQL4
DDX54
-
-
DHX58
DDX51
RECQL
DHX37
DDX20
-
DDX47
-
-
-
-
DHX29
DHX9

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.