Oryctolagus_cuniculusFamily: DEAD Number of Genes: 75
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
SMARCA1
DHX36
DDX23
DHX16
DDX39A
-
DDX24
ASCC3
IFIH1
DDX50
DDX21
DHX15
DDX55
DDX10
-
-
DDX42
-
DHX29
MTREX
DDX25
DDX58
DHX33
DDX17
EIF4A2
RAD54L
DDX6
-
DDX60
DHX30
DDX1
SKIV2L
FANCM
POLQ
DHX37
DDX4
DDX31
RECQL
-
-
DDX54
DHX38
SNRNP200
EIF4A1
DICER1
-
-
YTHDC2
DDX46
DDX3X
-
WRN
SMARCA5
DHX58
HELQ
BLM
DDX47
DDX52
DHX9
TDRD9
DHX57
DDX27
RECQL5
DDX59
-
-
-
-
-
DDX56
DDX28
-
DDX41
-
-
DDX39B
DDX51
CMSS1
-
-
DDX20
DDX5
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.