Panthera_tigris_altaicaFamily: DEAD Number of Genes: 70
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
SMARCA1
DHX37
-
-
DHX57
DDX18
ASCC3
SNRNP200
DDX28
DHX40
DDX59
DDX21
DDX4
DHX58
DDX19A
DICER1
DDX1
DDX50
RECQL
DDX17
-
ERCC6L2
-
-
MTREX
EIF4A3
DDX42
DHX29
DHX15
DDX10
DDX5
EIF4A2
DDX49
DDX55
DDX27
RAD54L
-
DDX46
DDX24
DDX52
DDX3X
DDX58
DHX30
-
BLM
DDX3Y
POLQ
DHX38
DDX39A
TDRD9
DDX39B
-
CMSS1
DHX36
DDX6
-
-
DDX23
HFM1
DDX25
DDX56
DDX47
DDX54
-
IFIH1
DDX41
RECQL5
WRN
SMARCA5
DHX9
HELQ
SKIV2L
YTHDC2
-
-
DDX60

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.