Mus_musculus_pwkphjFamily: MMR_HSR1 Number of Genes: 120
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Rab23
-
Eif5b
-
Arl4c
-
Sept2
-
Arl8a
-
Sept10
-
Sar1a
-
Rab36
-
-
-
Arl1
-
Drg1
-
Rab1a
-
Mtif2
-
Irgm1
-
-
-
-
-
Gm12185
-
Tgtp2
-
Ifi47
-
Sar1b
-
Sept8
-
Irgm2
-
Drg2
-
Eral1
-
Rab34
-
Sept4
-
Arl5c
-
Nkiras2
-
Rab5c
-
Rab37
-
Sept9
-
Dnajc27
-
Arl4a
-
Rab15
-
Arl10
-
Gfm2
-
Nkiras1
-
Gnl3
-
Rab2b
-
Arl11
-
Nuggc
-
Sept3
-
Rabl2
-
Arf3
-
Srl
-
Sept12
-
Sept5
-
Lsg1
-
Rabl3
-
Gtpbp8
-
Arl6
-
Arl13b
-
Rab44
-
Rab11b
-
Gnl1
-
Rab5a
-
Rab31
-
Rab12
-
Rab18
-
-
-
Rab1b
-
Arl2
-
Ehd1
-
Arl3
-
Arl5b
-
Rab14
-
Ola1
-
Ehd4
-
Rab22a
-
Arfrp1
-
Mfn1
-
Rab33b
-
Arl14
-
Rab25
-
Gimd1
-
Rab2a
-
Rasef
-
Rraga
-
Gnl2
-
Mfn2
-
Gtpbp10
-
Rheb
-
Gpn1
-
Guf1
-
Rasl11b
-
Noa1
-
Sept11
-
Gtpbp6
-
Rasl11a
-
Arf5
-
Gimap8
-
-
-
Gimap4
-
Gimap6
-
Gimap7
-
Gimap5
-
Rab7
-
Eefsec
-
Arl8b
-
Kras
-
Rasl2-9
-
Ehd2
-
Irgc1
-
Rab30
-
Rab6a
-
Sept1
-
Mtg1
-
Hras
-
Gtpbp3
-
Sept7
-
Rab11a
-
Rab6b
-
Srprb
-
Sept6
-
Rab33a
-
Rab39b
-
Arl13a
-
Rab9b
-
Gnl3l
-
Rab9
-

Introduction

Pfam

The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.

InterPro

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PUBMED:1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis [PUBMED:12429099]; ferrous iron transport protein B [PUBMED:20123128] and several others.

Reference

  1. Vernet C, Ribouchon MT, Chimini GPontarotti P; , Mamm Genome 1994;5:100-105.: Structure and evolution of a member of a new subfamily of GTP-binding proteins mapping to the human MHC class I region. PUBMED:8180467 EPMC:8180467 .

  2. Bassler J, Kallas M, Hurt E;, J Biol Chem. 2006;281:24737-24744.: The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. PUBMED:16803892 EPMC:16803892 .

  3. Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B;, Biochem Biophys Res Commun. 2009;379:201-205.: E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. PUBMED:19109926 EPMC:19109926 .

  4. Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P;, J Bacteriol. 2009;191:2307-2314.: Properties of HflX, an enigmatic protein from Escherichia coli. PUBMED:19181811 EPMC:19181811 .

  5. Shields MJ, Fischer JJ, Wieden HJ;, Biochemistry. 2009;48:10793-10802.: Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. PUBMED:19824612 EPMC:19824612.