Chrysemys_picta_belliiFamily: DEAD Number of Genes: 70
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
-
-
SKIV2L
EIF4A2
SMARCA1
DDX51
-
-
POLQ
ASCC3
-
-
-
DDX6
EIF4A1
DHX40
DHX58
HELQ
DDX58
DDX46
DDX24
RECQL
DDX5
BRIP1
DDX52
DICER1
DDX18
DDX25
-
DDX39A
DDX28
-
DDX49
DDX1
WRN
YTHDC2
-
FANCM
DHX30
DHX8
EIF4A3
DDX54
-
DHX36
DHX16
RECQL4
-
-
-
-
DDX23
TDRD9
-
-
DDX31
-
DDX20
DDX10
DDX41
SNRNP200
-
DHX57
-
DDX56
DHX37
BLM
DDX55
IFIH1
DDX4
MTREX
DHX29
DDX42
DDX27
DHX38
DDX60
SMARCA5
DHX15
RECQL5
DDX59

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.