Esox_luciusFamily: DEAD Number of Genes: 77
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
skiv2l
ddx46
-
ddx31
-
zgc:158828
helq
-
rad54l
ddx55
dhx57
ddx56
-
zgc:193690
mtrex
dhx29
ddx28
-
-
ddx59
ddx1
-
DDX5
ercc6l
dhx8
ddx18
dhx40
dhx37
ddx5
dhx36
ddx47
ddx24
eif4a1b
ddx20
dhx9
smarca1
DDX39A
tdrd9
recql
ddx43
ddx49
ddx54
ddx10
ddx27
ddx23
dhx16
-
-
YTHDC2
dhx15
recql5
ddx4
tdrd12
-
wrn
ddx39b
ddx52
dhx58
polq
-
eif4a3
ddx51
ddx21
hfm1
-
snrnp200
blm
DHX15 (1 of many)
cmss1
-
DDX41
ifih1
dhx33
ddx61
ddx42
dhx30
recql4
-
ddx6
ascc3
-
eif4a2
dicer1
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.