Labrus_bergyltaFamily: DEAD Number of Genes: 75
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
ddx19 (1 of many)
ddx21
ddx61
DDX39A
-
-
dhx58
ddx42
-
-
ifih1
tdrd12
-
ddx28
-
cmss1
-
zgc:158828
hfm1
-
ddx43
ddx31
eif4a2
ddx1
dicer1
ascc3
DDX5
zgc:193690
dhx8 (1 of many)
ddx10
-
-
-
ddx39b
-
-
SMARCA1
ddx19 (1 of many)
rad54l
ddx52
recql4
-
-
dhx30
-
-
-
dhx16
ddx6
smarca5
blm
-
eif4a1b
recql5 (1 of many)
ddx20
recql5 (1 of many)
mtrex
ddx23
ddx54
ddx4
dhx15
eif4a3
ddx24
snrnp200
ddx55
-
-
helq (1 of many)
tdrd9
ddx59
ddx27
-
ddx5
DDX18
dhx36
recql
dhx37
-
ddx51
ddx56
dhx38
-
ddx18
ddx46
ddx49
YTHDC2
DDX41
dhx57
ddx47

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.