Latimeria_chalumnaeFamily: DEAD Number of Genes: 71
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
EIF4A3
SNRNP200
DDX58
DDX21
ddx43
-
DHX57
-
-
DHX8
DDX39B
TDRD9
-
-
-
eif4a1a
recql4
-
DDX28
DDX24
CHD1L
BLM
-
SMARCA5
DHX15
FANCM
-
ddx3xa
DDX46
DDX31
-
DDX49
DICER1
DHX40
DDX54
MTREX
CMSS1
DHX30
-
DDX59
DDX1
-
-
HFM1
-
HELQ
YTHDC2
DDX51
DHX29
DHX58
IFIH1
-
RECQL
DDX27
RECQL5
-
-
DDX52
DHX37
DDX41
DDX42
DDX47
-
-
DHX34
DDX5
DDX39A
ddx61
ascc3
-
DDX18
DDX56
DHX36
SMARCA1
DDX23
DDX55
DDX6
DDX60
DDX25
-
DHX9
-
eif4a2
DHX33
DDX20
ddx19

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.