Bos_taurusFamily: DEAD Number of Genes: 69
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
EIF4A1
DDX49
SNRNP200
POLQ
SMARCA1
DDX10
FANCM
DDX58
SMARCA5
DDX24
DDX31
DDX19A
DDX25
DDX28
SKIV2L
DHX36
DDX27
DHX16
DDX55
IFIH1
DDX4
DHX15
DDX6
DDX17
DDX1
DDX52
DHX29
MTREX
DDX56
RECQL5
DDX54
DICER1
DHX38
YTHDC2
DDX39B
DDX21
DHX57
EIF4A2
-
DDX41
DHX30
EIF4A3
DDX51
DHX40
HELQ
-
DDX5
DDX20
DDX47
DHX9
RAD54L
BLM
TDRD9
DHX37
ASCC3
DDX59
DDX19B
HFM1
DDX42
RECQL
DDX46
WRN
DDX23
-
DDX39A
-
-
DDX50
DDX3X
DHX58
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.