Sarcophilus_harrisiiFamily: DEAD Number of Genes: 73
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
RAD54L
-
-
FANCM
HLTF
SNRNP200
-
DDX25
-
-
DHX33
DHX29
YTHDC2
DDX39B
DDX17
MTREX
-
-
DDX39A
WRN
DDX50
-
DHX58
HELQ
DDX23
DHX30
POLQ
DHX16
-
-
-
-
-
BLM
-
-
SMARCA5
-
DHX9
SKIV2L
DDX24
DDX4
CMSS1
-
DDX1
-
DDX47
DDX49
DDX6
DHX15
-
-
DDX51
DICER1
DDX5
-
DDX52
-
DDX46
DDX20
-
-
DDX59
DHX57
DDX54
EIF4A1
RECQL
DDX55
DDX60
DHX36
ASCC3
DDX56
DHX40
DHX38
-
-
EIF4A2
CHD1L
RECQL5
IFIH1
DDX18
DDX31

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.