Sus_scrofaFamily: DEAD Number of Genes: 75
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
DDX17
DDX23
RECQL
DHX16
DDX39B
SKIV2L
BLM
DDX24
TDRD9
-
DHX38
-
DHX34
RAD54L
-
ASCC3
FANCM
DDX31
TTF2
DDX20
HFM1
SNRNP200
DHX57
DDX1
DHX15
SMARCA5
HELQ
DDX60
DHX37
DDX55
DDX54
DDX50
DDX21
DHX30
EIF4A2
CMSS1
-
DDX3X
SMARCA1
YTHDC2
-
DDX6
DDX25
DDX18
WRN
IFIH1
DDX56
DHX29
MTREX
DDX4
EIF4A3
DDX42
DHX58
DHX40
EIF4A1
DDX52
DDX27
RECQL5
DDX59
DHX36
DDX49
RECQL4
DDX28
DDX3Y
DDX46
DHX9
DICER1
DDX51
DDX58
DDX5
DDX41
DDX47
-
-
POLQ
-
-

Introduction

Pfam

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

InterPro

Proteins with this domain include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.

Reference

  1. de la Cruz J, Kressler D, Linder P; , Trends Biochem Sci 1999;24:192-198.: Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. PUBMED:10322435 EPMC:10322435 .

  2. Aubourg S, Kreis M, Lecharny A; , Nucleic Acids Res 1999;27:628-636.: The DEAD box RNA helicase family in Arabidopsis thaliana. PUBMED:9862990 EPMC:9862990.